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H6878

Sigma-Aldrich

8-Hydroxychinolin

Synonym(e):

8-Hydroxychinolin, 8-Chinolinol, 8-Oxychinolin, Oxin

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About This Item

Empirische Formel (Hill-System):
C9H7NO
CAS-Nummer:
148-24-3
Molekulargewicht:
145.16
Beilstein:
114512
EG-Nummer:
205-711-1
MDL-Nummer:
MFCD00006807
UNSPSC-Code:
12352005
PubChem Substanz-ID:
24895771
NACRES:
NA.21

Assay

≥98.5%

Qualitätsniveau

200

Form

powder

mp (Schmelzpunkt)

72.5-74.0 °C

Wirkungsspektrum von Antibiotika

fungi

Wirkungsweise

DNA synthesis | interferes
enzyme | inhibits

SMILES String

Oc1cccc2cccnc12

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChIKey

MCJGNVYPOGVAJF-UHFFFAOYSA-N

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Allgemeine Beschreibung

Chemical structure: quinolone

Anwendung

Used as a lipophilic monoprotic bidentate chelating agent.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
049M4758V
049M4757V
SLCC1064
SLBX7482
SLBX7142

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8-Hydroxychinolin-β-D-glucuronid Natriumsalz ≥98.0% (HPLC)

Sigma-Aldrich

38153

8-Hydroxychinolin-β-D-glucuronid Natriumsalz

5,7-Dichlor-8-Chinolinol 99%

Sigma-Aldrich

D64600

5,7-Dichlor-8-Chinolinol

María Isabel Fernández-Bachiller et al.
Journal of medicinal chemistry, 53(13), 4927-4937 (2010-06-16)
Tacrine and PBT2 (an 8-hydroxyquinoline derivative) are well-known drugs that inhibit cholinesterases and decrease beta-amyloid (Abeta) levels by complexation of redox-active metals, respectively. In this work, novel tacrine-8-hydroxyquinoline hybrids have been designed, synthesized, and evaluated as potential multifunctional drugs for
Mahmud Tareq Hassan Khan et al.
Journal of medicinal chemistry, 52(1), 48-61 (2008-12-17)
In the present work, 22 compounds of the U.S. NCI compound library (size 273K) were identified as putative thermolysin binders by structure based virtual screening with the ICM software (ICM-VLS). In vitro competitive binding assays confirmed that 12 were thermolysin
Bhimashankar Mitkari et al.
Experimental neurology, 239, 158-162 (2012-10-13)
Cell therapies from various sources have been under intense research in stroke. Efficient homing of the cells to the injured brain without complications is necessary to realize the therapeutic potential of cell therapy. Intra-arterial (IA) infusion of cells bypasses the
David M Rubush et al.
Journal of the American Chemical Society, 134(33), 13554-13557 (2012-08-09)
The desymmetrization of p-peroxyquinols using a Brønsted acid-catalyzed acetalization/oxa-Michael cascade was achieved in high yields and selectivities for a variety of aliphatic and aryl aldehydes. Mechanistic studies suggest that the reaction proceeds through a dynamic kinetic resolution of the peroxy
Elke Debroye et al.
Dalton transactions (Cambridge, England : 2003), 41(35), 10549-10556 (2012-07-26)
A ditopic DTPA monoamide derivative containing an 8-hydroxyquinoline moiety was synthesized and the corresponding gadolinium(III) complex ([Gd(H5)(H(2)O)](-)) was prepared. After adding aluminum(III), the 8-hydroxyquinoline part self-assembled into a heteropolymetallic triscomplex [(Gd5)(3)Al(H(2)O)(3)](3-). The magnetic and optical properties of this metallostar compound
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