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H102

Supelco

Haloperidol-Metabolit II

analytical standard

Synonym(e):

(±)-4-(4-Chlorphenyl)-α-(4-fluorphenyl)-4-hydroxy-1-piperidinbutanol, Haloperidol, reduziert

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About This Item

Empirische Formel (Hill-System):
C21H25ClFNO2
CAS-Nummer:
34104-67-1
Molekulargewicht:
377.88
MDL-Nummer:
MFCD00055102
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329815151
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

solid

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Farbe

white

Löslichkeit

DMSO: 10 mg/mL

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

OC(CCCN1CCC(O)(CC1)c2ccc(Cl)cc2)c3ccc(F)cc3

InChI

1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2

InChIKey

WNZBBTJFOIOEMP-UHFFFAOYSA-N

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
FN09271904
027M4605V
078K4619
065K4624
034K4602

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

D W Eyles et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 8(2), 127-129 (1998-06-10)
In vitro, cytosolic human ketone reductases catalyse the stereospecific (i.e. >99%) formation of S(-) reduced haloperidol (RHP) from haloperidol (HP). Whether this situation is reflected in patients taking the drug is unknown. In this study in nine patients taking HP
W H Chang et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 4(2), 119-126 (1994-06-01)
Plasma haloperidol (HL) and reduced haloperidol (RH) levels were measured in 60 schizophrenic patients treated with high to very high HL doses of 40-200 mg/day. Plasma samples were obtained at steady-state conditions and 10-12 h after the evening dose and
Naoya Kishikawa et al.
Analytical and bioanalytical chemistry, 386(3), 719-724 (2006-09-08)
A simultaneous method for the determination of haloperidol (HP) and its metabolite, reduced haloperidol (RHP), in human serum was developed by means of high-performance liquid chromatography (HPLC) with fluorescence detection. Suzuki coupling reaction with a fluorescent arylboronic acid, 4-(4,5-diphenyl-1H-imidazol-2-yl)phenylboronic acid
M S Lee et al.
Psychiatry and clinical neurosciences, 52 Suppl, S193-S198 (1999-01-23)
Along with recent increased interest in the selective serotonin reuptake inhibitors, a number of studies has been undertaken to observe interactions with different drugs. When selective serotonin reuptake inhibitor was administered together with antipsychotics to schizophrenics showing depressive or obsessive
M Aravagiri et al.
Journal of chromatography. B, Biomedical applications, 656(2), 373-381 (1994-06-17)
A simple and highly sensitive liquid chromatographic method with electrochemical detection for the simultaneous determination of haloperidol and its metabolite reduced haloperidol in human plasma has been developed. The sample preparation for the analysis involves a simple one-step extraction procedure
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