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Merck

C0414

Supelco

Clidiniumbromid

analytical standard

Synonym(e):

3-Benziloyloxy-1-methyl-chinuclidinium-bromid, 3-[(Hydroxydiphenylacetyl)oxy]-1-methyl-1-azoniabicyclo[2.2.2]octan-bromid

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About This Item

Empirische Formel (Hill-System):
C22H26BrNO3
CAS-Nummer:
Molekulargewicht:
432.35
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

Br.C[N]12CCC(CC1)C(C2)OC(=O)C(O)(c3ccccc3)c4ccccc4

InChI

1S/C22H26NO3.BrH/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H

InChIKey

WVDSMJSQJXGCNY-UHFFFAOYSA-N

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Allgemeine Beschreibung

Clidinium bromide is an anticholinergic, antisecretory and antispasmodic drug, widely used in treating anxiety-related conditions and spastic colon by inhibiting the action of parasympathetic innervations thus decreasing the secretions of stomach acid and slowing the intestines.

Anwendung

Clidinium bromide has been used as an analytical standard for the quantification of the analyte in pharmaceutical formulations using different analytical techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Die Dokumentenbibliothek aufrufen

Simultaneous determination of clidinium bromide and chlordiazepoxide in combined dosage forms by high-performance liquid chromatography
Ashour S and Kattan N
Journal of pharmaceutics, 2013(1), 67-74 (2013)
D Le Guludec et al.
Circulation, 90(1), 172-178 (1994-07-01)
Decreased myocardial adenylate cyclase activity in response to guanine nucleotide stimulation has been recently demonstrated in denervated myocardium of transplant patients, suggesting that changes in left ventricular muscarinic receptors may occur. The concentration and affinity constants of myocardial muscarinic receptors
H Yazawa et al.
The Journal of urology, 152(6 Pt 1), 2173-2177 (1994-12-01)
We obtained a primary culture of prostatic cells by an explant method from patients with benign prostatic hypertrophy (BPH). Ultrastructural morphology and growth characteristics of these cells conformed to those reported for smooth muscle cells isolated from vascular and visceral
F Brunner et al.
British journal of pharmacology, 102(2), 373-380 (1991-02-01)
1. Muscarinic receptors on endothelial cells of bovine thoracic aorta were characterized by binding assays in which (-)-[3H]-N-methyl quinuclidinyl benzilate ([3H]-NMeQNB) was used as radioligand. 2. Binding of [3H]-NMeQNB to crude membranes of freshly isolated endothelial cells was atropine-displaceable and
Simultaneous determination of chlordiazepoxide and clidinium bromide in pharmaceutical formulations by derivative spectrophotometry
Toral I.M, et al.
The Veterinary Quarterly, 189(1), 67-74 (1999)

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