BP583

Meptazinol -hydrochlorid

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): 3-(3-ethylhexahydro-1-methyl-1H-azepin-3-yl)-phenol hydrochloride, IL-22811 hydrochloride, WY-22811 hydrochloride
• Empirische Formel (Hill-System): C₁₅H₂₃NO· HCl
• CAS-Nummer: 59263-76-2
• Molekulargewicht: 269.81
• EG-Nummer: 261-683-0
• MDL-Nummer: MFCD00941476
• UNSPSC-Code: 41116107

Eigenschaften

• Qualität: pharmaceutical primary standard; British Pharmacopoeia (BP) Reference Standard
• API-Familie: meptazinol
• Form: solid
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: BP
• Anwendung(en): pharmaceutical
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: Cl.CCC1(CCCCN(C)C1)c2cccc(O)c2
• InChI: 1S/C15H23NO.ClH/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13;/h6-8,11,17H,3-5,9-10,12H2,1-2H3;1H
• InChIKey: MPJUSISYVXABBH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Meptazinol hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Meptazinol Injection

Meptazinol Tablets

Biochem./physiol. Wirkung

Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound.

Verpackung

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 + P330 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable