37022

(−)-Scopolamin -hydrochlorid

analytical standard

• Synonym(e): Hyoscin -hydrochlorid, Scopin-tropat
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · HCl
• CAS-Nummer: 55-16-3
• Molekulargewicht: 339.81
• Beilstein: 4168778
• EG-Nummer: 200-225-6
• MDL-Nummer: MFCD00058096
• UNSPSC-Code: 85151701
• PubChem Substanz-ID: 329755587
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): cleaning products; cosmetics; food and beverages; personal care
• Format: neat
• Lagertemp.: −20°C
• SMILES String: Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
• InChIKey: KXPXJGYSEPEXMF-MOUKNHLCSA-N
• Angaben zum Gen: human ... CHRM1(1128)

Beschreibung

Allgemeine Beschreibung

(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest, found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.

For the analysis of the phytotoxins.

Anwendung

(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species using various chromatographic techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Kompetitiver, nichtselektiver muskarinischer Acetylcholin-Antagonist. Scopolamin-induzierte Amnesie bei Labortieren ist ein häufig verwendetes Modell von Gedächtnis-Defizit.

Rekonstituierung

Dried down, Konzentratio von (S)-(-)-Scopolamine (freie Base) nach Rücklösung 100 μg/mL

Hinweis zur Analyse

purity : ≥96.0% (HPLC)

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330,H317,H318
• P-Sätze: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable