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03920590

Oleanolsäure

primary reference standard

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About This Item

Empirische Formel (Hill-System):
C30H48O3
CAS-Nummer:
508-02-1
Molekulargewicht:
456.70
EG-Nummer:
208-081-6
MDL-Nummer:
MFCD00064914
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329747839
NACRES:
NA.24

Qualität

primary reference standard

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

HWI

mp (Schmelzpunkt)

>300 °C (lit.)

Anwendung(en)

food and beverages

SMILES String

[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1

InChIKey

MIJYXULNPSFWEK-GTOFXWBISA-N

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Allgemeine Beschreibung

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

Reference Standard in the analysis of herbal medicinal products

Biochem./physiol. Wirkung

Triterpenoid isolated from medicinal plants. Antitumor and hepatoprotective agent. Oleanolic acid has therapeutic potential for neurodegenerative diseases.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
HWI01611-2
HWI01611-1
HWI01611
HWI00684-1

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Ursolsäure ≥90%

Sigma-Aldrich

U6753

Ursolsäure

Liangfeng Fu et al.
Organic letters, 15(7), 1622-1625 (2013-03-28)
Bardoxolone methyl (2-cyano-3,12-dioxooleane-1,9(11)-dien-28-oic acid methyl ester; CDDO-Me) (1), a synthetic oleanane triterpenoid with highly potent anti-inflammatory activity (levels below 1 nM), has completed a successful phase I clinical trial for the treatment of cancer and a successful phase II trial
Dick de Zeeuw et al.
The New England journal of medicine, 369(26), 2492-2503 (2013-11-12)
Although inhibitors of the renin-angiotensin-aldosterone system can slow the progression of diabetic kidney disease, the residual risk is high. Whether nuclear 1 factor (erythroid-derived 2)-related factor 2 activators further reduce this risk is unknown. We randomly assigned 2185 patients with
Philippe Charlier et al.
Scientific reports, 3, 1296-1296 (2013-03-02)
During the Middle Ages, the partition of the cadaver of the elite members was a current practice, with highly technical treatment given to symbolic organs such as the heart. Considered mostly from a theoretical point of view, this notion of
Min Song et al.
Journal of pharmaceutical and biomedical analysis, 40(1), 190-196 (2005-08-30)
A highly selective and sensitive HPLC-ESI-MS-MS method was developed for the determination of oleanolic acid in human plasma. The oleanolic acid and glycyrrhetinic acid (internal standard) were recovered from plasma with ethyl acetate liquid-liquid extraction. The organic extracts were dried
Fei Yu et al.
Journal of medicinal chemistry, 56(11), 4300-4319 (2013-05-15)
Development of hepatitis C virus (HCV) entry inhibitors represents an emerging approach that satisfies a tandem mechanism for use with other inhibitors in a multifaceted cocktail. By screening Chinese herbal extracts, oleanolic acid (OA) was found to display weak potency
Alle zugehörigen Dokumente anzeigen

Protokolle

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Effective analysis of passion flower by HPTLC fingerprinting, in conjunction with a comprehensive range of related reference materials, enables fast and efficient identification of this plant material.

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