02150595

Osthol

primary reference standard

• Synonym(e): 7-Methoxy-8-(3-methyl-2-butenyl)-cumarin, 7-Methoxy-8-isopentenylcumarin, Osthol
• Empirische Formel (Hill-System): C₁₅H₁₆O₃
• CAS-Nummer: 484-12-8
• Molekulargewicht: 244.29
• MDL-Nummer: MFCD00076049
• UNSPSC-Code: 85151701
• PubChem Substanz-ID: 329747396
• NACRES: NA.24

Eigenschaften

• Qualität: primary reference standard
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: HWI
• Anwendung(en): food and beverages
• SMILES String: COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C
• InChI: 1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
• InChIKey: MBRLOUHOWLUMFF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

Reference Standard in the analysis of herbal medicinal products

Biochem./physiol. Wirkung

Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable