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Key Documents

MABT42

Sigma-Aldrich

Anti-Integrin beta-2 (CD18) Antibody, clone M18/2

clone M18/2, from rat

Synonym(e):

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), integrin beta chain, beta 2, complement receptor C3 beta-subunit, leukocyte cell adhesion molecule CD18, integrin beta-2, Complement receptor C3 subunit beta, Cell surface adhesion glyco

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rat

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

M18/2, monoclonal

Speziesreaktivität

mouse

Methode(n)

flow cytometry: suitable
immunoprecipitation (IP): suitable

Isotyp

IgG2aκ

NCBI-Hinterlegungsnummer

NP_032430

UniProt-Hinterlegungsnummer

P11835

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Itgb2(16414)

Allgemeine Beschreibung

Integrin beta-2, also known as CD18, is an adhesion receptor in neutrophils that interacts with cytohesin-1 intracellularly. Integrin beta is instrumental in activation-dependent adhesion and adhesion-dependent signaling. Expression of integrin beta-2 has a positive correlation with patient survival from malignant B cell lymphoma.

Immunogen

Whole B10 mouse spleen cells enriched with T-cells.

Anwendung

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Sanchez-Madrid, F., et al. (1983). J. ExP. MED. 158:586-602).

Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466).
This Anti-Integrin beta-2 (CD18) Antibody, clone M18/2 is validated for use in FC, IP for the detection of Integrin beta-2 (CD18).

Qualität

Evaluated by Flow Cytometry in mouse EL4 cells.

Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells.

Zielbeschreibung

85 kDa calculated

Physikalische Form

Format: Purified

Hinweis zur Analyse

Control
Mouse EL4 cells

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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