MABS31

Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2

clone CPTC-Calcyclin-2, from mouse

• Synonym(e): S100 calcium binding protein A6, S100 calcium binding protein A6 (calcyclin), protein S100-A6, calcyclin, S100 calcium-binding protein A6 (calcyclin), Growth factor-inducible protein 2A9, Calcyclin, Prolactin receptor-associated protein, S100 calcium-bin
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: CPTC-Calcyclin-2, monoclonal
• Speziesreaktivität: human
• Methode(n): ELISA: suitable; immunohistochemistry: suitable; western blot: suitable
• Isotyp: IgG2aκ
• NCBI-Hinterlegungsnummer: NP_055439
• UniProt-Hinterlegungsnummer: P06703
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... S100A6(6277)

Beschreibung

Allgemeine Beschreibung

Calcyclin, also known as S100A6, is a calcium binding protein that is highly expressed in fibroblasts and epithelial cells. Inhibition of calcyclin by p53 is part of the mechanism to control cell proliferation. Calcyclin is associated with cancer and metastasis and plays a role in cell cycle regulation.

Immunogen

Full length recombinant protein corresponding to human Calcyclin.

Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
GPCR-, cAMP/cGMP- & kalziumabhängige Signalübertragung

Anti-Calcyclin Antibody, clone CPTC-Calcyclin-2 detects level of Calcyclin & has been published & validated for use in WB, ELISA, IH.

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (Tara Hitke, Developmental Studies Hybridoma Bank, University of Iowa.)

Qualität

Evaluated by Western Blot in human lung tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Calcyclin on 10 µg of human lung tissue lysate.

Zielbeschreibung

~10 kDa observed

Physikalische Form

Protein G

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Human lung tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable