MAB5320
Anti-Synuclein α Antibody, clone 7B12.2
culture supernatant, clone 7B12.2, Chemicon®
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(3)
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Antikörperform
culture supernatant
Antikörper-Produkttyp
primary antibodies
Klon
7B12.2, monoclonal
Speziesreaktivität
human
Hersteller/Markenname
Chemicon®
Methode(n)
immunohistochemistry: suitable
western blot: suitable
Isotyp
IgG
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... SNCA(6622)
Spezifität
Reacts with alpha Synuclein. By Western blot the antibody shows no reactivity with beta or gamma synuclein. This antibody was shown to stain Lewy bodies in frozen section of human brain with Parkinson′s disease and glial inclusions in frozen section of human brain with Multiple System Atrophy.
Immunogen
Recombinant human alpha synuclein.
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten
Neurodegenerative Krankheiten
Anti-Synuclein Antibody, α, clone 7B12.2 detects level of Synuclein & has been published & validated for use in IH & WB.
Western blotting on recombinant alpha synuclein: 1:2,000-1:4,000.
Lane 1: Recombinant human alpha synuclein
Lane 2: Recombinant human beta synuclein
Lane 3: Recombinant human gamma synuclein
Immunohistochemistry (frozen sections): 1:250-1:500
Optimal working dilutions must be determined by end user.
Lane 1: Recombinant human alpha synuclein
Lane 2: Recombinant human beta synuclein
Lane 3: Recombinant human gamma synuclein
Immunohistochemistry (frozen sections): 1:250-1:500
Optimal working dilutions must be determined by end user.
Zielbeschreibung
15-18 kDa
Verlinkung
Replaces: 04-1053
Physikalische Form
Unpurified
UnPurified tissue culture supernatant from a perfusion system, filtered through a 0.2μ micron membrane prior to vialing. Product contains 20%FBS and Ciprofloxacin at final concentration of 10μg/mL.
Lagerung und Haltbarkeit
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hinweis zur Analyse
Control
Brain tissue
Brain tissue
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Sie haben nicht das passende Produkt gefunden?
Probieren Sie unser Produkt-Auswahlhilfe. aus.
Empfehlung
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Kristina R Patterson et al.
The Journal of biological chemistry, 286(26), 23063-23076 (2011-05-10)
Neurofibrillary tangles, composed of insoluble aggregates of the microtubule-associated protein Tau, are a pathological hallmark of Alzheimer disease (AD) and other tauopathies. However, recent evidence indicates that neuronal dysfunction precedes the formation of these insoluble fibrillar deposits, suggesting that earlier
Francesca Sardone et al.
Journal of cellular physiology, 229(7), 878-886 (2013-12-21)
Cell-extracellular matrix interaction plays a major role in maintaining the structural integrity of connective tissues and sensing changes in the biomechanical environment of cells. Collagen VI is a widely expressed non-fibrillar collagen, which regulates tissues homeostasis. The objective of the
Xichen Zheng et al.
The Journal of clinical investigation, 128(5), 2104-2115 (2018-04-18)
Immune checkpoint blockade (ICB) has demonstrated curative potential in several types of cancer, but only for a small number of patients. Thus, the identification of reliable and noninvasive biomarkers for predicting ICB responsiveness is an urgent unmet need. Here, we
Lithium protects against oxidative stress-mediated cell death in ?-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease.
Kim, YH; Rane, A; Lussier, S; Andersen, JK
Journal of Neuroscience Research null
Lu-Yao Tong et al.
Frontiers in pharmacology, 13, 914153-914153 (2022-07-23)
The recovery of spinal cord injury (SCI) is closely associated with the obstruction of oligodendrocyte progenitor cell (OPC) differentiation, which ultimately induces the inability to generate newly formed myelin. To address the concern, drug-based methods may be the most practical
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.