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MAB416

Sigma-Aldrich

Anti-Interferon-β Antibody, clone A1

clone A1, Chemicon®, from mouse

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

A1, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

Isotyp

IgGκ

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... IFNB1(3456)

Spezifität

Human interferon-beta (IFN-beta). Recognizes amino acids 30-47 of IFN-beta. No cross-reactivity with Human IFN-alpha or IFN-gamma.

Immunogen

Human interferon beta.

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Cytokine & Cytokin-Rezeptoren
Anti-Interferon-β Antibody, clone A1 detects level of Interferon-β & has been published & validated for use in ELISA & WB.
Immunoblotting

ELISA

Neutralization of IFN-beta bioactivity; 90% reduction of bioactivity at 1.4 μg/mL for recombinant IFN-beta and 2.7 μg/mL for natural IFN-beta. Assay method used is provided in Grossberg, S.E. et al, Manual of Clinical Immunology.

Optimal working dilutions must be determined by the end user.

Physikalische Form

Format: Purified
Hybridoma culture grown in low IgG FBS (3%), Protein G purified. Liquid in 50 mM Na Acetate, pH 6.5, 50 mM NaCl, 4% sucrose, 0.1% Tween20, no preservatives added

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to twelve months after date of receipt. Avoid repeated freeze/thaw cycles.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Neutralizing antibodies to interferon beta in multiple sclerosis: analytical evaluation for validation of a cytopathic effect assay.
Catherine Massart,Jacqueline Gibassier,Joel Oger,Emmanuelle Le Page,Gilles Edan
Clinica Chimica Acta; International Journal of Clinical Chemistry null
Analysis of antigenic domains on natural and recombinant human IFN-beta by the inhibition of biologic activities with monoclonal antibodies.
Redlich, P N and Grossberg, S E
Journal of immunology (Baltimore, Md. : 1950), 143, 1887-1893 (1989)
Reduced effectiveness of long-term interferon-beta treatment on relapses in neutralizing antibody-positive multiple sclerosis patients: a Canadian multiple sclerosis clinic-based study.
C Boz,J Oger,E Gibbs,S E Grossberg,
Multiple Sclerosis (Houndmills, Basingstoke, England) null
Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3.
Susan E Sweeney,Ling Mo,Gary S Firestein
Arthritis and Rheumatism null

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