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Merck

MAB1912

Sigma-Aldrich

Anti-Procollagen Type I Antibody, NT, clone M-58

culture supernatant, clone M-58, Chemicon®

Synonym(e):

Anti-Procollagen Antibody, Clone M-58 Anti-Procollagen, Type I Procollagen Detection

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rat

Qualitätsniveau

Antikörperform

culture supernatant

Klon

M-58, monoclonal

Speziesreaktivität

human

Darf nicht reagieren mit

rat, hamster, mouse

Hersteller/Markenname

Chemicon®

Methode(n)

immunohistochemistry: suitable (paraffin)

Isotyp

IgG2α

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... COL1A1(1277)

Spezifität

Recognizes Human pro-collagen I. MAB1912 labels the amino-terminal pro-peptide.

Anwendung

Detect Procollagen Type I using this Anti-Procollagen Type I Antibody, N-terminus, clone M-58 validated for use in IH(P).
Immunohistochemistry: 1:10,000-1:50,000 (fresh frozen tissue sections.)

Suitable for formaldehyde/formalin fixed paraffin sections, suggested starting dilution 1:100-1:1000, after treatment with 1% trypsin, 20 minutes at room temperature. Does not stain mature collagen fibers in tissue. Localized intracellularly in cells producing pro-collagen I. Not recommended for Western Blots Optimal working dilutions must be determined by end user.

Hinweis zur Analyse

Control
Skin tissue

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2


Analysenzertifikate (COA)

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International Journal of Cancer. Journal International Du Cancer null
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Danielsen, Patricia L, et al.
Annals of Surgery, 251, 825-831 (2010)
Dose-dependent impairment of collagen deposition by topical granulocyte-macrophage colony-stimulating factor in human experimental wounds.
Lars N Jorgensen, Magnus S Agren, S?ren M Madsen, Finn Kallehave, Faranak Vossoughi et al.
Annals of Surgery null
M D Rekhter et al.
The American journal of pathology, 143(6), 1634-1648 (1993-12-01)
Because collagen is a major component of the human atherosclerotic plaque, factors controlling collagen synthesis may have a profound influence on the volume growth of these intimal lesions. In human arteries, we compared normal vs atherosclerotic media vs intimas for
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