FCMAB255F

Milli-Mark^® Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

clone TC11-18H10.1, Milli-Mark^®, from rat

• Synonym(e): Cytotoxic T-lymphocyte-associated antigen 8
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rat
• Konjugat: FITC conjugate
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: TC11-18H10.1, monoclonal
• Speziesreaktivität: mouse
• Hersteller/Markenname: Milli-Mark^®
• Methode(n): flow cytometry: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NP_034682
• UniProt-Hinterlegungsnummer: Q62386
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: mouse ... Il17A(16171)

Beschreibung

Allgemeine Beschreibung

IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.

Spezifität

Antibody recognizes Interleukin-17A.

Immunogen

Recombinant protein corresponding to mouse Il17a

Anwendung

Research Category
Entzündung & Immunologie

Research Sub Category
Immunologische Signalübertragung

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.

Qualität

Evaluated by flow cytometry using stimulated EL-4 cells

Zielbeschreibung

17 kDa Calculated

Physikalische Form

Antigen Affinity Purified

Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Hinweis zur Analyse

Control
PMA and Ionomycin stimulated EL-4 cells.

Rechtliche Hinweise

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable