CBL158
Anti-Integrin β2 [CD18] Antibody
clone MEM 48, Chemicon®, from mouse
Synonym(e):
CD18
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Antikörperform
purified antibody
Antikörper-Produkttyp
primary antibodies
Klon
MEM 48, monoclonal
Speziesreaktivität
human
Hersteller/Markenname
Chemicon®
Methode(n)
flow cytometry: suitable
immunohistochemistry: suitable
western blot: suitable
Isotyp
IgG1
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Angaben zum Gen
human ... ITGB2(3689)
Spezifität
This antibody recognizes the CD18 molecule, a 95 kDa integrin molecule (beta 2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins which are expressed on all leucocytes. The beta2 integrin is the ICAM 1 receptor
FUSION PARTNER:
Sp 2/0 - Ag 14 myeloma cell line
FUSION PARTNER:
Sp 2/0 - Ag 14 myeloma cell line
Immunogen
Leucocytes from an LGL - type leukaemia
Anwendung
Research Category
Zellstruktur
Zellstruktur
Research Sub Category
Integrine
Integrine
Anti-Integrin β2 [CD18] Antibody detects level of Integrin β2 [CD18] & has been published & validated for use in FC, WB, IH.
Immunohistochemistry: Identification of CD18+ leucocytes on cryostat sections
Function Blocking: Studies of cell-cell and cell-matrix adhesion, this antibody will block cell-cell interaction, (Grönholm, 2018)
Flow Cytometry
Western Blot
Optimal working dilutions must be determined by the end user.
Function Blocking: Studies of cell-cell and cell-matrix adhesion, this antibody will block cell-cell interaction, (Grönholm, 2018)
Flow Cytometry
Western Blot
Optimal working dilutions must be determined by the end user.
Verlinkung
Replaces: CBL514
Physikalische Form
Format: Purified
The monoclonal is presented in phosphate buffered saline containing 15mM sodium azide, pH 7.4. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Lagerung und Haltbarkeit
Maintain at 2o-8oC for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Sie haben nicht das passende Produkt gefunden?
Probieren Sie unser Produkt-Auswahlhilfe. aus.
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
K Drbal et al.
Biochemical and biophysical research communications, 275(2), 295-299 (2000-08-31)
Monoclonal antibodies to CD18, the common chain of leukocyte integrins, recognize in various types of human lymphoid and myeloid cells under the conditions of nonreducing Western blotting three species of CD18 of mol. wt. 96, 87, and 78 kDa, respectively.
The role of galectin-3 in phagocytosis of Candida albicans and Candida parapsilosis by human neutrophils.
Linden, JR; Kunkel, D; Laforce-Nesbitt, SS; Bliss, JM
Cellular Microbiology null
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein.
Bazil, V, et al.
Folia Biologica (Praha.), 36, 41-50 (1990)
Structure and function of leukocyte integrins.
Larson, R S and Springer, T A
Immunological Reviews, 114, 181-217 (1990)
Association of the CD59 and CD55 cell surface glycoproteins with other membrane molecules
Stefanova, I and Horejsi, V
Journal of immunology (Baltimore, Md. : 1950), 147, 1587-1592 (1991)
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.