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Merck

AB3542

Sigma-Aldrich

Anti-Monocarboxylate Transporter 2 Antibody

serum, Chemicon®

Synonym(e):

MCT2

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SLC16A7(9194)

Spezifität

Recognizes rat Monocarboxylate Transporter 2 (MCT2). The immunogen shows no significant sequence homology with other MCT.

The immunogen sequence is 93% conserved in mouse and 66% in hamster. Reactivity with other species has not been confirmed.

Immunogen

A 15 amino acid peptide sequence near the C-terminus of rat MCT2 (Jackson et al. 1997; Dao et al. 1998; Koehler-Stec et al. 1998; Price et al. 1998; Halestrap & Price 1999).

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Ionenkanäle & -transporter
Anti-Monocarboxylate Transporter 2 Antibody is an antibody against Monocarboxylate Transporter 2 for use in ELISA & WB.
Western blot

ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog number AG218) per well.

Optimal working dilutions must be determined by the end user.

Verlinkung

Replaces: AB3542P

Physikalische Form

Rabbit serum. Liquid.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

R Y Lin et al.
The Journal of biological chemistry, 273(44), 28959-28965 (1998-10-24)
The transport of pyruvate and lactate across cellular membranes is an essential process in mammalian cells and is mediated by the H+/monocarboxylate transporters (MCTs). We have molecularly cloned and characterized a novel human monocarboxylate transporter, MCT2. The cDNA is 1,907
Estrogen Receptor Involvement in Noradrenergic Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neurotransmitter and Stimulus-Specific Glycogen Phosphorylase Enzyme Isoform Expression.
A S M H Mahmood et al.
ASN neuro, 12, 1759091420910933-1759091420910933 (2020-04-03)
Emmanuel Cruz et al.
Glia, 70(11), 2207-2231 (2022-08-03)
The consumption of glucose in the brain peaks during late childhood; yet, whether and how glucose metabolism is differentially regulated in the brain during childhood compared to adulthood remains to be understood. In particular, it remains to be determined how
Estrogen Receptor Involvement in Noradrenergic Regulation of Ventromedial Hypothalamic Nucleus Glucoregulatory Neurotransmitter and Stimulus-Specific Glycogen Phosphorylase Enzyme Isoform Expression.
A S M H Mahmood et al.
ASN neuro, 12, 1759091420910933-1759091420910933 (2020-04-03)
Thomas Philips et al.
Cell reports, 34(2), 108610-108610 (2021-01-14)
Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axonal degeneration. However, it is unknown how widespread

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