AB3442

Anti-CREB Antibody, pSer133

serum, Chemicon^®

• Synonym(e): CREB-1, cAMP-response Element-binding Protein-1
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: serum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Speziesreaktivität: mouse, human, monkey, rat
• Hersteller/Markenname: Chemicon^®
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NM_004379.2; NM_134442.2
• UniProt-Hinterlegungsnummer: P16220
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CREB1(1385)

Beschreibung

Spezifität

Recognizes phosphorylated Serine133 in cAMP response element binding protein (CREB). By immunoblotting the antibody shows a 5-10 fold increase in staining of a 43 kDa protein after treatment of cells with agents that increase intracellular cAMP. The antibody also recognizes phosphorylated ATF-1 due to a common epitope. The antibody has been preabsorbed with unphosphorylated peptide and will prove to be useful for the investigation of CREB phosphorylation.

Immunogen

Epitope: pSer133

Phosphopeptide conjugated to KLH.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen

Research Sub Category
Transkriptionsfaktoren

RNA-Bindeproteine (RBP)

Anti-CREB Antibody, pSer133 is a Rabbit Polyclonal Antibody for detection of CREB also known as CREB-1, cAMP-response Element-binding Protein-1 & has been validated in WB.

Immunoblotting: 1:500-1:1,000

Optimal working dilutions must be determined by the end user.

Physikalische Form

Rabbit serum. Liquid. The antibody has been preabsorbed with unphosphorylated peptide. Contains 0.01% sodium azide.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1