575001

α-Synuclein, Human, Recombinant, E. coli

• Synonym(e): NACP
• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: human
• Qualitätsniveau: 100
• Rekombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: liquid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; avoid repeated freeze/thaw cycles
• Eignung: suitable for molecular biology
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... SNCA(6622)

Beschreibung

Allgemeine Beschreibung

Research area: Neuroscience

Recombinant, human α-synuclein expressed in E. coli. α-Synuclein is an acidic neuronal protein of 140 amino acids (amino acid residues 1 -140).

Anwendung

α-Synuclein, Human, Recombinant, E. coli has been used to enhance the filter trap assay for identification of aggregated alpha-synuclein in brain samples.

Biochem./physiol. Wirkung

α-Synuclein been implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells.

Verpackung

Please refer to vial label for lot-specific concentration.

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM MgCl₂, pH 7.5.

Rekonstituierung

Following initial thaw, aliquot and freeze (-20°C).

Sonstige Hinweise

Kahle, P.J, et al. 2001. Am. J. Pathol.159, 2215.
Kim, J. 1997. Mol. Cells7, 78.
Paik, S.R. 1997. Arch. Biochem. Biophys.344, 325.
Jakes, R., et al. 1994. FEBS Lett.345, 27.
Ueda, K., et al. 1993. Proc. Natl. Acad. Sci. USA90, 11282.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable