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Key Documents

14-334-M

Sigma-Aldrich

PRAK Protein, active, 15 µg

Active, N-terminal His6-tagged recombinant, human, full-length PRAK, for use in Kinase Assays.

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About This Item

UNSPSC-Code:
12352200
eCl@ss:
32160405
NACRES:
NA.32

Biologische Quelle

human

Qualitätsniveau

100
300

Rekombinant

expressed in baculovirus infected Sf21 cells

Mol-Gew.

Mw 55 kDa

Hersteller/Markenname

Upstate®

Methode(n)

activity assay: suitable (kinase)

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Allgemeine Beschreibung

N-terminal His6-tagged recombinant, human, full-length PRAK
Product Source: expressed by baculovirus in Sf21 insect cells

Biochem./physiol. Wirkung

Protein Target: PRAK
Target Sub-Family: CAMK

Verpackung

Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-334M when ordering the 250μg size.

Qualität

routinely evaluated by phosphorylation of PRAK Substrate Peptide

Physikalische Form

Ni2+/NTA-agarose

Lagerung und Haltbarkeit

6 months at -70C

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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L New et al.
The EMBO journal, 17(12), 3372-3384 (1998-06-17)
We have identified and cloned a novel serine/ threonine kinase, p38-regulated/activated protein kinase (PRAK). PRAK is a 471 amino acid protein with 20-30% sequence identity to the known MAP kinase-regulated protein kinases RSK1/2/3, MNK1/2 and MAPKAP-K2/3. PRAK was found to
S P Davies et al.
The Biochemical journal, 351(Pt 1), 95-105 (2000-09-22)
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine/threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many

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