104662

Cellvento^® ModiFeed Sial+ COMP

Chemically defined cell culture feed - EMPROVE^® CCM

Eigenschaften

• Qualitätsniveau: 500
• Beschreibung: shipped with cooling packs
• Form: dry powder
• Methode(n): cell culture | mammalian: suitable
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Cellvento^® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento^® 4CHO and EX-CELL^® Advanced CHO or other production media.

Anwendung

Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento^® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes

Leistungsmerkmale und Vorteile

• Reduced complexity in fed-batch process
• Complete feed maximizing galactosylation
• Highly concentrated to reduce required feed volume
• Compacted format for conventient handling
• Higher liquid feed stability at room temperature

Menge

Formulated to contain 155.8 grams of powder per liter of feed.

Rechtliche Hinweise

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany