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Key Documents

07-543

Sigma-Aldrich

Anti-p19 ARF Antibody

Upstate®, from rabbit

Synonym(e):

Anti-ARF, Anti-CDK4I, Anti-CDKN2, Anti-CMM2, Anti-INK4, Anti-INK4A, Anti-MLM, Anti-MTS-1, Anti-MTS1, Anti-P14, Anti-P14ARF, Anti-P16, Anti-P16-INK4A, Anti-P16INK4, Anti-P16INK4A, Anti-P19, Anti-P19ARF, Anti-TP16

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

rat, mouse

Hersteller/Markenname

Upstate®

Methode(n)

immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

UniProt-Hinterlegungsnummer

Q8N726

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Cdkn2A(12578)
rat ... Cdkn2A(25163)

Spezifität

p19 ARF

Immunogen

Full length mouse p19 ARF fused to GST.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Zellzyklus, DNA-Replikation & -Reparatur
Detect p19 ARF with Anti-p19 ARF Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP & WB.

Qualität

Routinely evaluated by immunoblot with lysates from p53 knockout MEF cells.

Zielbeschreibung

19kDa

Physikalische Form

ImmunoAffinity Purified

Lagerung und Haltbarkeit

2 years at -20°C from date of shipment

Hinweis zur Analyse

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Shubhankar Suman et al.
Aging, 5(8), 607-622 (2013-08-10)
Despite recent epidemiological evidences linking radiation exposure and a number of human ailments including cancer, mechanistic understanding of how radiation inflicts long-term changes in cerebral cortex, which regulates important neuronal functions, remains obscure. The current study dissects molecular events relevant
p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Ying Qi, Mark A Gregory, Zhaoliang Li, Jeffrey P Brousal, Kimberly West, Stephen R Hann
Nature null
Hui-Yi Kua et al.
Nature cell biology, 14(7), 727-737 (2012-06-26)
Defects in stem cell renewal or progenitor cell expansion underlie ageing-related diseases such as osteoporosis. Yet much remains unclear about the mechanisms regulating progenitor expansion. Here we show that the tyrosine kinase c-Abl plays an important role in osteoprogenitor expansion.
S Kitajima et al.
Oncogene, 30(6), 737-750 (2010-10-05)
The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) gene had been isolated as an antagonist to RAS signaling; however, the mechanism of its action is not clear. In this study, the effect of loss of RECK function was assessed in
Nicolas Jullien et al.
PloS one, 10(3), e0120010-e0120010 (2015-03-31)
To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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