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Merck
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07-337

Sigma-Aldrich

Anti-SOS1 Antibody, CT

Upstate®, from rabbit

Synonym(e):

Anti-Anti-GF1, Anti-Anti-GGF1, Anti-Anti-GINGF, Anti-Anti-HGF, Anti-Anti-NS4, Anti-Anti-SOS-1

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

mouse, human

Hersteller/Markenname

Upstate®

Methode(n)

immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_005633

UniProt-Hinterlegungsnummer

Q07889

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SOS1(6654)

Spezifität

SOS1

Immunogen

peptide corresponding to amino acids 1243-1258 (KKSDHGNAFFPNSPSP) of murine Son of Sevenless Homolog 1 Protein (SOS 1)

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
MAP-Kinasen
Anti-SOS1 Antibody, CT is an antibody against SOS1 for use in IP & WB.

Qualität

routinely evaluated by immunoblot on 3T3/A31, A431 cell lysates, or HeLa nuclear extracts

Zielbeschreibung

175 kDa

Physikalische Form

Protein A chromatography
Format: Purified
Protein A purified Rabbit Ig in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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J Ng et al.
The Journal of biological chemistry, 272(39), 24542-24549 (1997-09-26)
Interleukin 2 (IL-2) induces tyrosine phosphorylation of STATs 3 and 5 (signal transducer and activator of transcription). We now show that IL-2 regulation of STAT3 proteins in T cells is a complex response involving activation of two forms of STAT3:
T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.
Zhao, H, et al.
The Journal of Biological Chemistry, 272, 21625-21634 (1997)
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