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Key Documents

05-170

Sigma-Aldrich

Anti-IL-2 Rα Antibody, clone 7G7/B6

clone 7G7/B6, Upstate®, from mouse

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

7G7/B6, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

dot blot: suitable
immunocytochemistry: suitable

Isotyp

IgG2a

NCBI-Hinterlegungsnummer

NM_000417.1

UniProt-Hinterlegungsnummer

P01589

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... IL2RA(3559)

Spezifität

Recognizes interleukin-2 receptor.

Immunogen

Whole cells expressing human IL-2 Receptor α

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Cytokine & Cytokin-Rezeptoren
This Anti-IL-2 Rα Antibody, clone 7G7/B6 is validated for use in DB, IC for the detection of IL-2 Rα.

Qualität

routinely evaluated on ice cold ethanol/acetic acid [95:5] fixed phytohemagglutinin (PHA)-treated Jurkat T lymphocytes

Zielbeschreibung

55 kDa

Physikalische Form

Protein G Purified
Format: Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide as a preservative.

Lagerung und Haltbarkeit

Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C

Hinweis zur Analyse

Control
Lung tissue

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.
Rubin, L A, et al.
Hybridoma, 4, 91-102 (1985)
P D Tahiliani et al.
The Journal of biological chemistry, 272(12), 7892-7898 (1997-03-21)
Integrin-mediated adhesion of cells to extracellular matrix proteins triggers a variety of intracellular signaling pathways including a cascade of tyrosine phosphorylations. In many cell types, the cytoplasmic focal adhesion tyrosine kinase, FAK, appears to be the initial protein that becomes
K S Lai et al.
The Journal of biological chemistry, 270(42), 25028-25036 (1995-10-20)
Signal transduction of cytokine receptors is mediated by the JAK family of tyrosine kinases. Recently, the kinase partners for the interleukin (IL)-2 receptor have been identified as JAK1 and JAK3. In this study, we report the identification of splice variants
Junya Tomida et al.
Nucleic acids research, 41(14), 6930-6941 (2013-06-01)
When DNA replication is stalled at sites of DNA damage, a cascade of responses is activated in the cell to halt cell cycle progression and promote DNA repair. A pathway initiated by the kinase Ataxia teleangiectasia and Rad3 related (ATR)
Kevin Lu et al.
Cancer research, 77(11), 2881-2892 (2017-04-19)
NRF2 is a transcription factor serving as a master regulator of the expression of many genes involved in cellular responses to oxidative and other stresses. In the absence of stress, NRF2 is constantly synthesized but maintained at low levels as
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