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Key Documents

05-1567

Sigma-Aldrich

Anti-p120 Catenin Antibody, clone 15D2

clone 15D2, from mouse

Synonym(e):

Cadherin-associated Src substrate, catenin (cadherin-associated protein), delta 1, catenin, delta 1, p120 catenin

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

15D2, monoclonal

Speziesreaktivität

mouse, human

Speziesreaktivität (Voraussage durch Homologie)

rat

Methode(n)

flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable

Isotyp

IgG1κ

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CTNND1(1500)

Allgemeine Beschreibung

p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.

Spezifität

Recognizes p120 Catenin

Immunogen

Epitope: C-terminus
Recombinant fusion protein derived from the C-terminus of murine p120

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Transkriptionsfaktoren
Immunocytochemistry:
Use Anti-p120 Catenin Antibody, clone 15D2 (mouse monoclonal antibody) validated in WB, ICC, FC to detect p120 Catenin also known as Cadherin-associated Src substrate ,catenin (cadherin-associated protein) delta 1.

Qualität

Evaluated by Western Blot on Hela cell lysate.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.

Zielbeschreibung

90-120 kDa

Verlinkung

Replaces: 04-237

Physikalische Form

Protein G Chromatography
Format: Purified
Purified mouse monoclonal in 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.

Hinweis zur Analyse

Control
Hela cell lysate.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

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International journal of molecular sciences, 21(7) (2020-04-11)
The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing
Lindy J Pence et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Inflammatory breast cancer is a highly aggressive form of breast cancer that forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. These cancers express high levels of E-cadherin, the major mediator of adherens junctions, which enhances formation of

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