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Merck

M-083

Supelco

Methylphenidat -hydrochlorid -Lösung

(Racemic mixture), ampule of 1 mL, 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C14H20ClNO2
CAS-Nummer:
Molekulargewicht:
269.77
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material

Qualitätsniveau

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

Konzentration

1.0 mg/mL in methanol (as free base)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

forensics and toxicology

Format

single component solution

Lagertemp.

2-8°C

SMILES String

Cl.COC(=O)C(C1CCCCN1)c2ccccc2

InChI

1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H

InChIKey

JUMYIBMBTDDLNG-UHFFFAOYSA-N

Angaben zum Gen

Allgemeine Beschreibung

Methylphenidate is a psychostimulant prescribed for treatment of attention-deficit hyperactivity disorder (ADHD), tachycardia and narcolepsy. This Certified Spiking Solution® is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology and forensic analysis. Methylphenidate is sold under trade names Concerta® and Ritalin®.

Anwendung


  • Methylphenidate HCl solution in ADHD pharmacotherapy studies: Research published in "Molecular Psychiatry" explored the effects of methylphenidate on Drosophila brain at single-cell resolution, highlighting its potential for ADHD treatment repurposing and its impact on neurotransmitter regulation (Qu et al., 2023).

  • CNS stimulant research with high-purity methylphenidate HCl: A case study in "Children (Basel)" detailed the complex relationship between ADHD symptoms and self-induced weight loss in a child, underscoring methylphenidate′s role in managing hyperkinetic disorders and its potential interactions with eating behaviors (Mestermann et al., 2023).

  • Neuropharmacology Methylphenidate in neurotransmitter research: A review in "Molecular Biotechnology" discussed the pharmacological applications of amino acids, using methodologies that could be applied to substances like methylphenidate for enhanced understanding of its interaction with brain chemistry and neurotransmitter functions (Kamaraj and Vuppu, 2023).

  • Liquid methylphenidate for in vitro neuropharmacology studies: An analysis in "Journal of Medical Internet Research" investigated the nonmedical use and adverse effects of methylphenidate, providing insights into its impact during the COVID-19 pandemic and highlighting the importance of monitoring drug usage trends for improved public health strategies (Shin et al., 2023).

  • Dopamine reuptake inhibitor research with methylphenidate solution: A report in "Journal of Analytical Toxicology" detailed a case of fatal intoxication where methylphenidate′s properties as a dopamine reuptake inhibitor were considered in the context of its toxicological profile, emphasizing the need for careful monitoring of its use and effects (Ameline et al., 2023).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Concerta is a registered trademark of ALZA Corporation
Ritalin is a registered trademark of Novartis Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes,Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Methylphenidate: trismus.
Prescrire international, 22(140), 185-185 (2013-08-21)
Methylphenidate vs atomoxetine: personalized medicine in attention- deficit/hyperactivity disorder.
Hartmut Heinrich et al.
JAMA psychiatry, 70(5), 545-545 (2013-05-03)
Liv Larsen Stray et al.
Behavioral and brain functions : BBF, 9, 18-18 (2013-05-07)
Most children who are diagnosed with attention deficit-hyperactivity disorder (ADHD) have moderate-to-severe motor problems using the Motor Function Neurological Assessment battery (MFNU). The MFNU focuses on specific muscle adjustment problems associated with ADHD, especially motor inhibition problems and high muscle
Evert J Semeijn et al.
Journal of the American Geriatrics Society, 61(6), 882-887 (2013-05-29)
To increase insight into the effect of attention-deficit/hyperactivity disorder (ADHD) on health in general in older adults. Two-phase sampling side-study. Longitudinal Aging Study Amsterdam (LASA). Two hundred twenty-three randomly selected LASA respondents. Information was collected during home visits on physical
Methylphenidate in the management of cancer-related fatigue.
Patrick C Stone
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(19), 2372-2373 (2013-05-22)

Artikel

As a major metabolite of methylphenidate (1, Ritalin), ±-threo-Ritalinic acid (2) is of clinical relevance.

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