H-004

Hydromorphon -Lösung

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₁₇H₁₉NO₃
• CAS-Nummer: 466-99-9
• Molekulargewicht: 285.34
• EG-Nummer: 200-659-6
• MDL-Nummer: MFCD00864214
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329815100
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• Konzentration: 1 mg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): forensics and toxicology
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: CN1CC[C@@]23[C@H]4CCC(=O)[C@@H]2Oc5c(O)ccc(C[C@@H]14)c35
• InChI: 1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1
• InChIKey: WVLOADHCBXTIJK-YNHQPCIGSA-N
• Angaben zum Gen: human ... OPRM1(4988)

Beschreibung

Allgemeine Beschreibung

A certified reference standard suitable for use as a starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis, clinical toxicology, and pain prescription monitoring to urine drug testing and pharmaceutical research. Hydromorphone, marketed under brand names including Palladone and Dilaudid^®, is a very potent opioid analgesic. The drug is often used medicinally as an alternative to morphine for treatment of pain or as a cough suppressant for painful coughing resulting from continued bronchial irritation.

Anwendung

• Quantitative analysis of Haloperidol: Development of a sensitive LC-MS/MS method for Haloperidol quantification in human plasma, employing Haloperidol-D₄ as an internal standard and incorporating phospholipid removal pretreatment to enhance detection accuracy (Zidekova et al., 2021).


• Automated determination in toxicological studies: Utilization of Haloperidol-D₄ in an automated method for toxicokinetic studies of Trimebutine and its metabolites, demonstrating the compound′s role in high-throughput forensic toxicology (Larabi et al., 2015).


• High-throughput drug monitoring: Application of ′high throughput′ solid-phase extraction and turbo ionspray LC-MS-MS for Haloperidol determination in plasma, showcasing the efficiency of Haloperidol-D₄ as a stable isotope-labeled standard for enhancing bioanalytical procedures (Hempenius et al., 1999).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Dilaudid is a registered trademark of Purdue Pharma L.P.

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup