LM2144

Sphingosine-1-Phosphate (d17:1)

Avanti Research^™ - A Croda Brand

• Synonym(e): heptadeca-sphing-4-enine-1-phosphate
• Empirische Formel (Hill-System): C₁₇H₃₆NO₅P
• CAS-Nummer: 474923-27-8
• Molekulargewicht: 365.45
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: ethanol solution
• Verpackung: pkg of 1 × 1 mL (LM2144-1EA)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Konzentration: ~10 μg/mL (Refer to C of A for lot specific concentration.)
• Anwendung(en): lipidomics; metabolomics
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O
• InChI: 1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1
• InChIKey: VITGNIYTXHNNNE-LHMZYYNSSA-N

Beschreibung

Allgemeine Beschreibung

Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals and is produced in endothelial cells. It is a cellular metabolite and signalling lipid in mammalian cells. S1P is synthesized by sphingosine kinases from sphingosine. It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).

Biochem./physiol. Wirkung

Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes. It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes. S1P regulates skin dendritic cells and keratinocytes

Verpackung

2 mL Amber Glass Sealed Ampule (LM2144-1EA)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H319
• P-Sätze: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 55.4 °F - closed cup
• Flammpunkt (°C): 13.0 °C - closed cup