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Merck

890870C

Avanti

16:0 TAP

Avanti Research - A Croda Brand 890870C

Synonym(e):

1,2-dipalmitoyl-3-trimethylammonium-propane (chloride salt)

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About This Item

Empirische Formel (Hill-System):
C38H76NO4Cl
CAS-Nummer:
Molekulargewicht:
646.47
MDL-Nummer:
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

liquid

Verpackung

pkg of 1 × 2.5 mL (890870C-25mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 890870C

Konzentration

10 mg/mL (890870C-25mg)

Lipid-Typ

cationic lipids
transfection

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Cl-]

InChI

1S/C38H76NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-37(40)42-35-36(34-39(3,4)5)43-38(41)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h36H,6-35H2,1-5H3;1H/q+1;/p-1

Allgemeine Beschreibung

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is a cationic lipid and a diol based transfection reagent.

Anwendung

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) is suitable to prepare lipid monolayer/liposome:
  • to mimic the presence of the cationic charge localized in the membrane for understanding the electrostatic effects in the biological membranes and to study its interaction with zearalenone and selenate ions
  • to study its effect on the L-pro catalyzed reaction
  • to serve as a positive control, to determine the effectiveness of anionic phospholipids for pro-inflammatory responses

Biochem./physiol. Wirkung

1,2-dipalmitoyl-3-trimethylammonium-propane (16:0 TAP) liposomes are known to promote elevated pro-inflammatory responses.

Verpackung

5 mL Clear Glass Sealed Ampule (890870C-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system, Liver,Kidney

WGK

WGK 3


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In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)

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