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870202O

Avanti

18:1 PDP PE

Avanti Research™ - A Croda Brand 870202O

Synonym(e):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate] (sodium salt)

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About This Item

Empirische Formel (Hill-System):
C49H84N2O9PNaS2
CAS-Nummer:
474944-13-3
Molekulargewicht:
963.29
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

liquid

Verpackung

pkg of 1 × 25 mg (870202O-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 870202O

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H][C@@](COP([O-])(OCCNC(CCSSC1=CC=CC=N1)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C49H85N2O9PS2.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36-48(53)57-43-45(60-49(54)37-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)44-59-61(55,56)58-41-40-50-46(52)38-42-62-63-47-35-33-34-39-51-47;/h17-20,33-35,39,45H,3-16,21-32,36-38,40-44H2,1-2H3,(H,50,52)(H,55,56);/q;+1/p-1/b19-17-,20-18-;/t45-;/m1./s1

InChIKey

LFMWVVNPVNIPJG-JQRYTBKHSA-M

Allgemeine Beschreibung

18:1 PDP PE, also referred as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate], is a head group modified functionalized lipid. Functionalized lipids mainly act as reporter molecules.

Anwendung

18:1 PDP PE may be used in the preparation of hydrophobized disulfide-linked oligodeoxyribonucleotide (ODN). It may also be used in the preparation of liposomes.

Verpackung

5 mL Clear Glass Sealed Ampule (870202O-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Pathways for modulating exosome lipids identified by high-density lipoprotein-like nanoparticle binding to scavenger receptor type B-1
Angeloni NL, et al.
Scientific reports, 6(1) (2016)
Disulfide-linked liposomes: effective delivery vehicle for Bcl-2 antisense oligodeoxyribonucleotide G3139
Weecharangsan W, et al.
Anticancer Research, 30(1), 31-37 (2010)
Hitchhiking nanoparticles: Reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes
Wayteck L, et al.
Biomaterials, 77, 243-254 (2016)
Laura Wayteck et al.
Biomaterials, 77, 243-254 (2015-11-26)
Following intravenous injection of anti-cancer nanomedicines, many barriers need to be overcome en route to the tumor. Cell-mediated delivery of nanoparticles (NPs) is promising in terms of overcoming several of these barriers based on the tumoritropic migratory properties of particular
Lindsay Scheetz et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(16), 4369-4380 (2020-05-23)
Gliomas are brain tumors with dismal prognoses. The standard-of-care treatments for gliomas include surgical resection, radiation, and temozolomide administration; however, they have been ineffective in providing significant increases in median survival. Antigen-specific cancer vaccines and immune checkpoint blockade may provide
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