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Merck

850530O

Avanti

7.7 MAG

Avanti Research - A Croda Brand 850530O

Synonym(e):

1-(7Z-tetradecenoyl)-rac-glycerol

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About This Item

Empirische Formel (Hill-System):
C17H32O4
CAS-Nummer:
Molekulargewicht:
300.43
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

oil

Mol-Gew.

300.43 g/mol

Verpackung

pkg of 10 × 0.1 g (with screw cap (850530O-1g))
pkg of 2 × 100 mg (with screw cap (850530O-200mg))
pkg of 5 × 100 mg (with screw cap (850530O-500mg))

Hersteller/Markenname

Avanti Research - A Croda Brand 850530O

Methode(n)

protein sequencing: suitable

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

Monoacylglycerols (MAGs) are glycerol esters. 7.7 MAG has a 14 carbon acyl chain and possess a bilayer thickness of 25.8 Å.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Anwendung

7.7 MAG may be used as a host lipid in MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex for crystallization by lipidic cubic phase (LCP) method.

Biochem./physiol. Wirkung

Monoacylglycerols (MAGs) are used in food industry as emulsifiers. 7.7 MAG participates in meso crystallization of BtuB (vitamin B12 transporter), an outer membrane protein. It can also help in lysozyme crystal growth. 7.7 MAG also plays a key role in the growth of diffraction-quality crystals. MAGs holds high significance in pharmaceutical and food industry.

Verpackung

5 mL PTFE Vial with Screw Cap (850530O-1g)
5 mL PTFE Vial with Screw Cap (850530O-200mg)
5 mL PTFE Vial with Screw Cap (850530O-500mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Kai Yu Chen et al.
Journal of agricultural and food chemistry, 67(29), 8191-8196 (2019-07-10)
Conversion of free fatty acids into monoacylglycerol gives rise to new structural properties, particularly amphipathic property. Therefore, monoacylglycerols are widely used in pharmaceutical and food industries and are also reported to facilitate better absorption into the human body. A functional
Protein
Johner N, et al.
Journal of the American Chemical Society, 136, 3271-3271 (2014)
Lisa V Misquitta et al.
Structure (London, England : 1993), 12(12), 2113-2124 (2004-12-04)
Monoacylglycerols have been used as bilayered hosts for growing crystals of membrane proteins. To date, the lipids used have had chains 16 and 18 carbon atoms long. We hypothesized that a shorter-chained lipid producing a thinner bilayer would facilitate the
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that

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