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Merck

850399C

Avanti

24:1 (Cis) PC

1,2-dinervonoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(e):

1,2-di-(15Z-tetracosenoyl)-sn-glycero-3-phosphocholine; PC(24:1(15Z)/24:1(15Z)); 110930

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About This Item

Empirische Formel (Hill-System):
C56H108NO8P
CAS-Nummer:
Molekulargewicht:
954.43
UNSPSC-Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

Form

liquid

Verpackung

pkg of 1 × 2.5 mL (850399C-25mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 850399C

Konzentration

10 mg/mL (850399C-25mg)

Lipid-Typ

cardiolipins
phospholipids

Versandbedingung

dry ice

Lagertemp.

−20°C

InChI

1S/C56H108NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-46-48-55(58)62-52-54(53-64-66(60,61)63-51-50-57(3,4)5)65-56(59)49-47-45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,54H,6-19,24-53H2,1-5H3/b22-20-,23-21-/t54-/m1/s1

InChIKey

REWNAIYQZZOESC-CGKZWXATSA-N

Allgemeine Beschreibung

Phosphatidylcholine (PC) is a zwitterionic glycerophospholipid. PC constitutes the major phospholipid in the eukaryotic membrane. Among bacteria, only 10% has PC in their membrane.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Anwendung

24:1 (Cis) PC is suitable for use as a phospholipid (PL) standard for lipid profiling of phosphatidylcholine by electrospray ionization mass spectrometry (ESI-MS/MS).
24:1 (Cis) PC has been used:
  • in the preparation of multivesicular liposomes (DepoFoam) formulation with protein or peptide drugs
  • in the formation of planar bilayer lipid membranes
  • for analyzing the phase transition of giant unilamellar dinervonoylphosphocholine (DNPC) vesicles by N-4-nitrobenz-2-oxa-1,3-diazol (NBD)-labelled fluorophore in confocal microscopy

Biochem./physiol. Wirkung

24:1 (Cis) PC is a synthetic lipid.
Phosphatidylcholine (PC) is essential for the structure and functions of eukaryotic membranes. PC is essential for very low-density lipoprotein synthesis in liver cells. PC is the substrate for sphingomyelin. PC is the major source of cell signaling molecules. PC is the structural component of many human parasites and helps in cell invasion.

Verpackung

5 mL Clear Glass Sealed Ampule (850399C-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system, Liver,Kidney

WGK

WGK 3


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Extraction and profiling of plant polar glycerol lipids
Liu Yu and Wang X
Bio-protocol (2016)
Observation of the main phase transition of dinervonoylphosphocholine giant liposomes by fluorescence microscopy
Metso AJ, et al.
Biochimica et Biophysica Acta - Biomembranes, 1713(2), 83-91 (2005)
Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore
Sobko AA, et al.
The Journal of Biological Chemistry, 281(20), 14408-14416 (2006)
[TM="DepoFoam"] technology: a vehicle for controlled delivery of protein and peptide drugs
Ye Q, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 64(1-3), 155-166 (2000)
Activating and deactivating roles of lipid bilayers on the Ca2+-ATPase/phospholamban complex
Gustavsson M, et al.
Biochemistry, 50(47), 10367-10374 (2011)

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