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810142C

Avanti

4ME 16:0 NBD PE (NBD-DPhPE)

1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt), chloroform

Synonym(e):

NBD-DPhPE

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About This Item

Empirische Formel (Hill-System):
C51H94N5O11P
CAS-Nummer:
1246355-56-5
Molekulargewicht:
984.29
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

liquid

Verpackung

pkg of 1 × 1 mL (810142C-1mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 810142C

Konzentration

1 mg/mL (810142C-1mg)

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

4ME 16:0 NBD PE (NBD-DPhPE) is a headgroup labeled fluorescent phospholipid.
NBD-DPhPE preferentially partitions, although not entirely, into the fluid phase of the cell membrane rather than the more ordered cholesterol and sphingolipid-enriched microdomain known as a lipid "raft."NBD-DSPE preferentially partitions, although not entirely, into the more ordered cholesterol and sphingolipid-enriched microdomain known as a lipid "raft." - Personal communication, Dr. Erwin London, SUNY-Stony Brook

Anwendung

4ME 16:0 NBD PE (NBD-DPhPE) or 1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt) may be used for fluorescence resonance energy transfer (FRET)experiments to determine raft affinity.

Verpackung

5 mL Amber Glass Screw Cap Vial (810142C-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system, Liver,Kidney

WGK

WGK 3

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Qingqing Lin et al.
Biophysical journal, 105(12), 2733-2742 (2013-12-24)
Because transmembrane (TM) protein localization, or nonlocalization, in ordered membrane domains (rafts) is a key to understanding membrane domain function, it is important to define the origin of protein-raft interaction. One hypothesis is that a tight noncovalent attachment of TM
Transmembrane Protein (Perfringolysin O) Association with Ordered Membrane Domains (Rafts) Depends Upon the Raft-Associating Properties of Protein-Bound Sterol
Lin Q and LondonE
Biophysical Journal, 105(12), 2733-2742 (2013)
Qingqing Lin et al.
The Journal of biological chemistry, 288(2), 1340-1352 (2012-11-15)
The hypothesis that mismatch between transmembrane (TM) length and bilayer width controls TM protein affinity for ordered lipid domains (rafts) was tested using perfringolysin O (PFO), a pore-forming cholesterol-dependent cytolysin. PFO forms a multimeric barrel with many TM segments. The
Peter J Quinn
Progress in lipid research, 49(4), 390-406 (2010-05-19)
Domains in cell membranes are created by lipid-lipid interactions and are referred to as membrane rafts. Reliable isolation methods have been developed which have shown that rafts from the same membranes have different proteins and can be sub-fractionated by immunoaffinity

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