H43806

4-Hydroxy-2-Methylchinolin

98.5%

• Synonym(e): 2-Methyl-4-chinolinol
• Empirische Formel (Hill-System): C₁₀H₉NO
• CAS-Nummer: 607-67-0
• Molekulargewicht: 159.18
• EG-Nummer: 210-140-6
• MDL-Nummer: MFCD00006758
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24895640
• NACRES: NA.22

Eigenschaften

• Assay: 98.5%
• SMILES String: Cc1cc(O)c2ccccc2n1
• InChI: 1S/C10H9NO/c1-7-6-10(12)8-4-2-3-5-9(8)11-7/h2-6H,1H3,(H,11,12)
• InChIKey: NWINIEGDLHHNLH-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:

• Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
• Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
• Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
• Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves