934569

NanoFabTx^™ Photoactivatable Lipid

redAzoPC

• Empirische Formel (Hill-System): C₄₆H₇₂Cl₄N₃O₈P
• CAS-Nummer: 2839130-47-9
• Molekulargewicht: 967.86
• UNSPSC-Code: 12161503
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥90%
• Form: solid
• Farbe: orange to dark red
• Lagertemp.: −20°C
• SMILES String: [O-]P(OCC[N+](C)(C)C)(OC[C@H](OC(CCCC1=CC(Cl)=C(C(Cl)=C1)/N=N/C2=C(C=C(C=C2Cl)CCCC)Cl)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C46H72Cl4N3O8P/c1-6-8-10-11-12-13-14-15-16-17-18-19-20-21-22-26-43(54)58-34-38(35-60-62(56,57)59-29-28-53(3,4)5)61-44(55)27-23-25-37-32-41(49)46(42(50)33-37)52-51-45-39(47)30-36(24-9-7-2)31-40(45)48/h30-33,38H,6-29,34-35H2,1-5H3/b52-51+/t38-/m1/s1
• InChIKey: FLGJQVLXMDITOI-MYZMGNDKSA-N

Beschreibung

Allgemeine Beschreibung

The NanoFabTx Photoactivatable Lipid, redAzoPC is a red-light photoswitchable lipid for controlled and targeted drug delivery. The tetra-ortho-chloro-azobenzene of redAzoPC can be isomerized from the cis to the trans conformation at 660 nm light. LNPs prepared using the NanoFabTx^™ Photoactivatable Lipid, redAzoPC result in controlled drug release following deep red light irradiation.

Anwendung

Lipid nanoparticle and liposome drug delivery systems

Leistungsmerkmale und Vorteile

• Similar drug loading, encapsulation efficiency, size, and polydispersity to non-photoswitchable lipids
• Light-induced drug delivery
• Targeted and controlled release
• Overcomes limitations associated to UV-switchable lipids

Rechtliche Hinweise

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable