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Merck

901237

Sigma-Aldrich

DHR Catalyst

greener alternative

≥95%

Synonym(e):

(2S,3R,4S)-2-Methyltetrahydro-2H-pyran-3,4-diol, Dihydrorhamnal

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About This Item

Empirische Formel (Hill-System):
C6H12O3
CAS-Nummer:
Molekulargewicht:
132.16
UNSPSC-Code:
12352201

Assay

≥95%

Form

powder or crystals

Eignung der Reaktion

reagent type: catalyst

Grünere Alternativprodukt-Eigenschaften

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Grünere Alternativprodukt-Kategorie

Lagertemp.

−20°C

SMILES String

[H]C1([H])C([H])([H])O[C@](C([H])([H])[H])([H])[C@@](O[H])([H])[C@@]1([H])O[H]

Allgemeine Beschreibung

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Anwendung

Dihydrorhamnal (DHR) catalyst was reported by the Morken Lab to be an effective carbohydrate-derived catalyst for enantioselective diboration of alkenes. Related capabilities were observed with the 6-tertbutyldimethylsilyl-1,2-dihydroglucal (TBS-DHG) catalyst( 901235 ).

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Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Die Dokumentenbibliothek aufrufen

Lichao Fang et al.
Journal of the American Chemical Society, 138(8), 2508-2511 (2016-02-09)
Catalytic enantioselective diboration of alkenes is accomplished with readily available carbohydrate-derived catalysts. Mechanistic experiments suggest the intermediacy of 1,2-bonded diboronates.
Carbohydrate/DBU Cocatalyzed Alkene Diboration: Mechanistic Insight Provides Enhanced Catalytic Efficiency and Substrate Scope
Yan L, et al.
Journal of the American Chemical Society, 140, 3663-3673 (2018)
Lu Yan et al.
Journal of the American Chemical Society, 140(10), 3663-3673 (2018-02-15)
A mechanistic investigation of the carbohydrate/DBU cocatalyzed enantioselective diboration of alkenes is presented. These studies provide an understanding of the origin of stereoselectivity and also reveal a strategy for enhancing reactivity and broadening the substrate scope.

Artikel

Enantioselective alkene diboration is a valuable strategy for transforming unsaturated hydrocarbons into useful chiral building blocks.

Verwandter Inhalt

Chiral organoboronic esters are well known as versatile intermediates for chemical synthesis. Not only are these compounds stable under a variety of reaction conditions, they are generally non-toxic and can be transformed with minimal generation of hazardous waste.

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