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Merck

900662

Sigma-Aldrich

Poly(D,L-lactide-co-glycolide)(85/15)-b-poly(ethylene glycol)-carboxylic acid

5k-13k

Synonym(e):

PLGA-PEG, PLGA-PEG Carboxylic acid diblock copolymer, PLGA-PEG-COOH, PLGA-b-PEG

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About This Item

Lineare Formel:
HO(CH(CH3)COO)x(CH2COO)y(CH2CH2O)nH
UNSPSC-Code:
12352106
NACRES:
NA.23

Qualitätsniveau

Form

solid

Lagertemp.

2-8°C

Anwendung

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic Poly(lactide-co-glycolide) (PLGA) block, functionalized with a terminal carboxylic acid. These materials have been used in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Additionally, the ratio of lactide to glycolide can be tuned to control rate of degradation. Carboxylic acid termination allows for facile further chemical modification of these materials.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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