79417

Phosphazen-Base P₂-Et

≥98.0% (NT)

• Synonym(e): 1-Ethyl-2,2,4,4,4-pentakis-(dimethylamino)-2λ⁵,4λ⁵-catenadi-(phosphazen), Tetramethyl-(tris-(dimethylamino)-phosphoranyliden)-phosphorictriamid-Et-imin
• Lineare Formel: [(CH₃)₂N]₃P=NP(=NC₂H₅)[N(CH₃)₂]₂
• CAS-Nummer: 165535-45-5
• Molekulargewicht: 339.40
• Beilstein: 7485991
• MDL-Nummer: MFCD00145113
• UNSPSC-Code: 12352000
• PubChem Substanz-ID: 57652793
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98.0% (NT)
• Form: liquid
• Brechungsindex: n20/D 1.492 (lit.); n20/D 1.492
• bp: 96 °C/0.05 mmHg (lit.)
• Dichte: 1.02 g/mL at 25 °C (lit.)
• SMILES String: CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C
• InChI: 1S/C12H35N7P2/c1-12-13-20(15(2)3,16(4)5)14-21(17(6)7,18(8)9)19(10)11/h12H2,1-11H3
• InChIKey: CFUKEHPEQCSIOM-UHFFFAOYSA-N

Beschreibung

Anwendung

Phosphazene Bases: a Family of Extremely Strong, Non-Ionic, Non-Charged Nitrogen–Bases

Phosphazene base P2-Et is an extremely strong, neutral nitrogen base. It gives excellent results where other bases fail

This strong non-ionic base has the ability to catalyze a wide variety of organic transformations such as:

• Palladium-catalyzed cross-coupling reactions when used in combination with tBuXPhos or tBuBrettPhos G3 precatalysts.
• Deprotonation of ortho-halobenzyl sulfones to generate α-sulfonyl benzylic carbanions.
• Conversion of vinyl sufone to allyl sulfone.
• α-Alkylation of 2-phenyl-2-oxazoline-4-carbonylcamphorsultam in the presence of tetrabutylammonium bromide.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter