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Merck

765430

Sigma-Aldrich

Gold nanoparticles

5 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Synonym(e):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

UNSPSC-Code:
12162002
NACRES:
NA.23

Materialien

PEG 3000

Qualitätsniveau

Form

dispersion in H2O
nanoparticles

Verpackung

poly bottle of 1 mL

OD

50

Durchmesser

5 nm

pH-Wert

6.0-8.0 (25 °C)

Löslichkeit

water: miscible

Dichte

1.00 g/cm3

λmax

515 nm

Funktionelle Gruppe

carboxylic acid

Lagertemp.

2-8°C

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Allgemeine Beschreibung

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

Anwendung

Carboxylic acid functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

Artikel

Biomaterials science involves the design and fabrication of smart materials for studying, directing, or mimicking biology. For successful integration of biomaterials in biological research, a meaningful understanding of biological systems is required.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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