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Merck

700312

Sigma-Aldrich

Eisenoxid(II,III), magnetische Nanopartikel -Lösung

10 nm avg. part. size, 5 mg/mL in toluene

Synonym(e):

Magnetische Eisenoxid Nanokristalle, Magnetit, Superparamagnetische Eisenoxid Nanopartikel

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About This Item

Empirische Formel (Hill-System):
Fe3O4
CAS-Nummer:
Molekulargewicht:
231.53
MDL-Nummer:
UNSPSC-Code:
12352302
PubChem Substanz-ID:
NACRES:
NA.23

Form

nanoparticles
solution

Konzentration

5 mg/mL in toluene

Magnetisierung

>45 emu/g (at ambient temperature under 4500 Oe)

Durchschnittliche Teilgröße

10 nm

Partikelgröße

9-11 nm (TEM; conforms)

Dichte

0.865 g/mL at 25 °C

SMILES String

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChIKey

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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Allgemeine Beschreibung

Iron oxide(II,III), magnetic nanoparticles solution (Fe3O4) is an organic solvent dispersed nanoparticle solution, which can be synthesized by the thermal decomposition of iron acetylacetonate in 2-pyrrolidone. It is majorly used in biomedical applications due to its magnetic properties, particle size, and surface properties.
It contains <1.0% oleic acid stabilizing ligands.
Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Anwendung

Fe3O4 can be used in the targeting and imaging of tumor cells for cancer therapy-based applications. It may also be used in the separation of tumor cells from fresh whole blood. It can also be used as an effective material in drug delivery systems and magnetic resonance imaging (MRI).

Signalwort

Danger

Gefahreneinstufungen

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 3

Flammpunkt (°F)

45.0 °F

Flammpunkt (°C)

7.2 °C

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Nonpolymeric coatings of iron oxide colloids for biological use as magnetic resonance imaging contrast agents
Portet D, et al.
Journal of Colloid and Interface Science, 238(1), 37-42 (2001)
Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system
Neuberger T, et al.
Journal of magnetism and magnetic materials, 293(1), 483-496 (2005)
Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood
Xu H, et al.
Biomaterials, 32(36), 9758-9765 (2011)
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy
Peng X, et al.
International journal of nanomedicine, 3(3), 311-311 (2008)
Synthesis of Fe3O4 nanoparticles with various sizes and magnetic properties by controlled hydrolysis
Iida H, et al.
Journal of Colloid and Interface Science, 314(1), 274-280 (2007)

Artikel

Currently, magnetic nanoparticles (MNPs) are attracting a lot of attention because of the possibility of many novel applications, especially in biomedical research.

A key challenge for nanomaterial safety assessment is the ability to handle the large number of newly engineered nanomaterials (ENMs), including developing cost-effective methods that can be used for hazard screening.

Graphene is a unique two-dimensional (2D) structure of monolayer carbon atoms packed into a dense honeycomb crystal that has attracted great interest due to its diverse and fascinating properties.

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.

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Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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