663190

Ethyl-5-Methylindol-2-Carboxylat

97%

• Synonym(e): 5-Methylindole-2-carboxylic acid ethyl ester, NSC 30928
• Empirische Formel (Hill-System): C₁₂H₁₃NO₂
• CAS-Nummer: 16382-15-3
• Molekulargewicht: 203.24
• MDL-Nummer: MFCD00022703
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24884618
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 160-164 °C
• Funktionelle Gruppe: ester
• SMILES String: CCOC(=O)c1cc2cc(C)ccc2[nH]1
• InChI: 1S/C12H13NO2/c1-3-15-12(14)11-7-9-6-8(2)4-5-10(9)13-11/h4-7,13H,3H2,1-2H3
• InChIKey: KMVFKXFOPNKHEM-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.

Anwendung

• Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions
• Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists
• Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents
• Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride
• Reactant for oximation reactions

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)