359351

3-Isochromanon

98%

• Empirische Formel (Hill-System): C₉H₈O₂
• CAS-Nummer: 4385-35-7
• Molekulargewicht: 148.16
• Beilstein: 123692
• EG-Nummer: 224-493-9
• MDL-Nummer: MFCD00043005
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24862071
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• mp (Schmelzpunkt): 80-82 °C (lit.)
• Funktionelle Gruppe: ester
• SMILES String: O=C1Cc2ccccc2CO1
• InChI: 1S/C9H8O2/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-4H,5-6H2
• InChIKey: ILHLUZUMRJQEAH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

3-Isochromanone has been reported to be isolated from the fungus Nigrospora sp. PSU-F12. An improved Knoevenagel condensation of 3-isochromanone with aromatic aldehydes has been achieved by microwave irradiation on solid supports in the presence of various catalysts. Synthesis of 3-isochromanone via Beayer-Villiger rearrangement has been reported.

Anwendung

3-Isochromanone may be used as starting reagent in the synthesis of of BDPBI (7-bromo-1,4-dihydro-2-phenyl-4,4-bis(4-pyridinylmethyl)2H-isoquinolin-3-one dihydrochloride).

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves