Alle Fotos(1)

Dokumente

286044

Harmin

Name: Harmin
Brand: ALDRICH

98%

Synonym(e):

7-Methoxy-1-methyl-9H-pyrido[3,4-b]indol

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):

C₁₃H₁₂N₂O

CAS-Nummer:

442-51-3

Molekulargewicht:

212.25

Beilstein:

178813

EG-Nummer:

207-131-4

MDL-Nummer:

MFCD00004958

UNSPSC-Code:

12352100

PubChem Substanz-ID:

24857229

NACRES:

NA.22

Assay

98%

mp (Schmelzpunkt)

262-264 °C (lit.)

SMILES String

CC1=NC=CC2=C1NC3=C2C=CC(OC)=C3

InChI

1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3

InChIKey

BXNJHAXVSOCGBA-UHFFFAOYSA-N

Angaben zum Gen

human ... CDC2(983) , CYP2D6(1565)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

The combination index (CI, serves as a quantitative indicator of pharmacological interactions) for harmaline/harmine and methylene blue/harmine was studied.

Anwendung

Harmine was used as a donor in the fluorescence resonance energy transfer (FRET) study between harmine and silver nanoparticles (AgNPs).

Biochem./physiol. Wirkung

Stimulant für das Zentralnervensystem

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

GHS07

Signalwort

Warning

H-Sätze

H302

P-Sätze

P264 - P270 - P301 + P312 - P501

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Inhibition of monoamine oxidase (MAO) by β-carbolines and their interactions in live neuronal (PC12) and liver (HuH-7 and MH1C1) cells.

Michael F Santillo et al.

Toxicology in vitro : an international journal published in association with BIBRA, 28(3), 403-410 (2014-01-01)

Interactions among monoamine oxidase (MAO) inhibitors in drugs, botanicals, and dietary supplements may lead to unpredictable neurochemical dysfunction due to excessive inhibition or therapeutic invalidation. Often recombinant MAO or brain tissue homogenates have been used to evaluate MAO inhibitors such

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma.

Katie L Uhl et al.

Cancer cell international, 18, 82-82 (2018-07-07)

Neuroblastoma (NB) is an early childhood malignancy that arises from the developing sympathetic nervous system. Harmine is a tricyclic β-carboline alkaloid isolated from the harmal plant that exhibits both cytostatic and cytotoxic effects. Harmine is capable of blocking the activities

Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.

Mansour Debdab et al.

Journal of medicinal chemistry, 54(12), 4172-4186 (2011-05-28)

We here report on the synthesis, optimization, and biological characterization of leucettines, a family of kinase inhibitors derived from the marine sponge leucettamine B. Stepwise synthesis of analogues starting from the natural structure, guided by activity testing on eight purified

Selective turn-on fluorescence assay of 6-thioguanine by using harmine-modified silver nanoparticles.

Mohammad Amjadi et al.

Luminescence : the journal of biological and chemical luminescence, 29(6), 689-694 (2013-11-30)

This article reports on a novel fluorescence resonance energy transfer (FRET) system between harmine and silver nanoparticles (AgNPs), in which harmine acts as the donor and AgNPs act as the acceptor. As a result of FRET, harmine fluorescence is quenched

The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro.

Jose A Morales-García et al.

Scientific reports, 7(1), 5309-5309 (2017-07-15)

Banisteriopsis caapi is the basic ingredient of ayahuasca, a psychotropic plant tea used in the Amazon for ritual and medicinal purposes, and by interested individuals worldwide. Animal studies and recent clinical research suggests that B. caapi preparations show antidepressant activity

Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.