284548

3,4-(Methylendioxy)toluol

97%

• Synonym(e): 5-Methyl-1,3-benzodioxol
• Empirische Formel (Hill-System): C₈H₈O₂
• CAS-Nummer: 7145-99-5
• Molekulargewicht: 136.15
• MDL-Nummer: MFCD00005833
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24857165
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: liquid
• Brechungsindex: n20/D 1.532 (lit.)
• bp: 199-200 °C (lit.)
• Dichte: 1.135 g/mL at 25 °C (lit.)
• SMILES String: Cc1ccc2OCOc2c1
• InChI: 1S/C8H8O2/c1-6-2-3-7-8(4-6)10-5-9-7/h2-4H,5H2,1H3
• InChIKey: GHPODDMCSOYWNE-UHFFFAOYSA-N

Beschreibung

Anwendung

3,4-(Methylenedioxy)toluene can be used as a cation scavenger for the selective cleavage of 4-(3,4-dimethoxyphenyl)benzyl (DMPBn) ethers affording the corresponding deprotected products in the presence of trifluoroacetic acid (TFA) in anhydrous CH₂Cl₂.
It can also be used as a starting material to prepare:

• 1,3-Benzodioxole-5-carboxaldehyde via photooxidation using CBr₄.
• 6-Methyl-1,3-benzodioxole-5-carboxaldehyde by treating with dichloromethylmethyl ether and TiCl₄.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H318
• P-Sätze: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 168.8 °F - closed cup
• Flammpunkt (°C): 76 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)