278823

4-Chlor-1-butanol

technical grade, ~85%

• Synonym(e): Tetramethylenchlorhydrin
• Lineare Formel: HO(CH₂)₄Cl
• CAS-Nummer: 928-51-8
• Molekulargewicht: 108.57
• Beilstein: 1731408
• MDL-Nummer: MFCD00002967
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24856834
• NACRES: NA.22

Eigenschaften

• Qualität: technical grade
• Assay: ~85%
• Form: liquid
• Brechungsindex: n20/D 1.453 (lit.)
• bp: 84-85 °C/16 mmHg (lit.)
• Dichte: 1.088 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro
• Lagertemp.: 2-8°C
• SMILES String: OCCCCCl
• InChI: 1S/C4H9ClO/c5-3-1-2-4-6/h6H,1-4H2
• InChIKey: HXHGULXINZUGJX-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.

Anwendung

4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.

Sonstige Hinweise

Contains tetrahydrofuran and HCl

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07
• Signalwort: Warning
• H-Sätze: H226,H290,H302,H315,H319,H335,H351
• P-Sätze: P202 - P210 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 96.8 °F - closed cup
• Flammpunkt (°C): 36 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter