269697

Ethyl-4,4,4-trifluorcrotonat

98%

• Synonym(e): 4,4,4-Trifluor-trans-2-butensäureethylester
• Lineare Formel: CF₃CH=CHCO₂C₂H₅
• CAS-Nummer: 406-10-0
• Molekulargewicht: 168.11
• MDL-Nummer: MFCD00009903
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24856340
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.3601 (lit.)
• bp: 114-115 °C (lit.)
• Dichte: 1.125 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: ester; fluoro
• SMILES String: CCOC(=O)\C=C\C(F)(F)F
• InChI: 1S/C6H7F3O2/c1-2-11-5(10)3-4-6(7,8)9/h3-4H,2H2,1H3/b4-3+
• InChIKey: ZKRJCMKLCDWROR-ONEGZZNKSA-N

Beschreibung

Allgemeine Beschreibung

The Michael reaction between ethyl 4,4,4-trifluorocrotonate and a Ni(II) complex of the Schiff base of glycine with (S)-o-[N-(N-benzylprolyl)amino]benzophenone was studied.

Anwendung

Ethyl 4,4,4-trifluorocrotonate was used in the synthesis of (2S,3S)-3-methyl- and (2S,3S)-3-trifluoromethylpyroglutamic acid. It undergoes diastereoselective Michael addition reaction with ethyl crotonate.

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Warning
• H-Sätze: H226,H319,H335
• P-Sätze: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 3 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 78.8 °F - closed cup
• Flammpunkt (°C): 26 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter