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1-Formyl-pyrrolidin
97%
Synonym(e):
Pyrrolidin-1-carbaldehyd
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About This Item
Empfohlene Produkte
Qualitätsniveau
Assay
97%
Form
liquid
Brechungsindex
n20/D 1.479 (lit.)
bp
92-94 °C/15 mmHg (lit.)
Dichte
1.04 g/mL at 25 °C (lit.)
SMILES String
[H]C(=O)N1CCCC1
InChI
1S/C5H9NO/c7-5-6-3-1-2-4-6/h5H,1-4H2
InChIKey
AGRIQBHIKABLPJ-UHFFFAOYSA-N
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Allgemeine Beschreibung
1-Formylpyrrolidine is the monomer constituent of gas clathrate inhibitor.
Anwendung
1-Formylpyrrolidine was used in the synthesis of 1-oxa-3,4-dimethyl-5-(1-pyrrolldino)-2,2-di(tert-butyl)silacyclopentane and 1-oxa-4-isopropyl-5-(1-pyrrolidino)-2,2-di(tert-butyl)silacyclopentane.
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
203.0 °F - closed cup
Flammpunkt (°C)
95 °C - closed cup
Persönliche Schutzausrüstung
Eyeshields, Gloves
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Preparation and synthetic utility of oxasilacyclopentane acetals derived from siliranes.
Tetrahedron, 53(48), 16597-16606 (1997)
Computational studies of structure and dynamics of clathrate inhibitor monomers in solution.
Industrial & Engineering Chemistry Research, 46(1), 131-142 (2007)
The Journal of organic chemistry, 68(25), 9747-9752 (2003-12-06)
N-Tritylprolinal (prepared in four steps from l-proline) shows a very high Felkin diastereoselectivity in its reaction with various nucleophiles, leading to a straightforward and highly stereoselective access to syn-proline-derived amino alcohols.
Journal of biochemistry, 98(4), 975-979 (1985-10-01)
The inhibitory effects of proline-containing peptides and their derivatives on prolyl endopeptidases from Flavobacterium meningosepticum and bovine brain were compared. Replacement of the carboxyl terminal proline in N-blocked peptides with prolinal resulted in remarkable decreases in Ki values for both
Journal of enzyme inhibition, 3(3), 163-178 (1990-01-01)
Several prolinal derivatives were synthesized and examined for their inhibitory activity on post-proline cleaving enzymes from Flavobacterium meningosepticum and bovine brain and their possible properties as nootropic agents. Almost all the compounds tested inhibited the activity of both enzymes at
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