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165344

Sigma-Aldrich

1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimidmethiodid

for peptide synthesis

Synonym(e):

EDC -methiodid

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About This Item

Lineare Formel:
C2H5N=C=N(CH2)3N(CH3)3I
CAS-Nummer:
22572-40-3
Molekulargewicht:
297.18
EG-Nummer:
245-095-1
MDL-Nummer:
MFCD00011833
UNSPSC-Code:
12352116
PubChem Substanz-ID:
24850134
NACRES:
NA.22

product name

1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimidmethiodid,

Form

powder

Qualitätsniveau

200

Eignung der Reaktion

reaction type: Coupling Reactions

mp (Schmelzpunkt)

97-99 °C (lit.)

Anwendung(en)

peptide synthesis

Funktionelle Gruppe

amine

Lagertemp.

2-8°C

SMILES String

[I-].CCN=C=NCCC[N+](C)(C)C

InChI

1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChIKey

AGSKWMRPXWHSPF-UHFFFAOYSA-M

Verwandte Kategorien

Anwendung

Water-soluble carboxyl modifying reagent for proteins.
  • Crosslinking agent

Reactant for:
  • Amide bond forming (amidation) crosslinking reactions

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCM9869
MKCH6550
MKCG7199
MKCC5614
MKBX8249V

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Cyrille Garnier et al.
Biochemistry, 41(39), 11770-11778 (2002-09-25)
The 90 kDa heat-shock protein (Hsp90) is one of the major stress proteins whose overall structure remains unknown. In this study, we investigated the influence of divalent cations Mg(2+) and Ca(2+) on the hydrodynamic properties and quaternary structure of Hsp90.
E Schaffitzel et al.
Biological chemistry, 382(8), 1235-1243 (2001-10-11)
In Escherichia coli, the ribosome-associated Trigger Factor (TF) cooperates with the DnaK system in the folding of newly synthesized cytosolic polypeptides. Here we investigated the functional relationship of TF and DnaK by comparing various functional properties of both chaperones. First
G Csaba et al.
Cell biology international, 30(5), 412-415 (2006-03-21)
The amount and localization of three hormones (histamine, endorphin and triiodothyronine [T(3)]) was measured in male and female rat peritoneal cells (lymphocytes, mast cells, monocyte-macrophage-granulocyte group [mo-gran]) using flow cytometry as well as confocal microscopy after paraformaldehyde (PFA) or EDAC
Q Paula Lei et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 813(1-2), 103-112 (2004-11-24)
An LC-MS/MS method for determination of the break down product of N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC) urea derivative, EDU, has been developed and validated for monitoring the residual coupling reagents. Results indicate that the method exhibits suitable specificity, sensitivity, precision, linearity and
Takahiro Kishimoto et al.
Biopolymers, 79(3), 163-172 (2005-08-12)
Pro-Hyp-Gly is a characteristic amino acid sequence found in fibrous collagens, and (Pro-Hyp-Gly)(10), which has been widely used as a collagen-model peptide, forms a stable triple-helical structure. Here, we synthesized polypeptides consisting of the Pro-Hyp-Gly sequence by direct poly-condensation of
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Artikel

Carbodiimide-mediated peptide coupling

Carbodiimide-mediated peptide coupling remains to the most frequently used technique.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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