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TLR7

toll-like receptor 7

Synonyme:
TLR7-like
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(51284) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170743) toll-like receptor 7
  • Rat(317468) toll-like receptor 7
  • cow(493686) toll-like receptor 7
  • sheep(554254) toll-like receptor 7
  • Goat(100860934) toll-like receptor 7
  • naked mole-rat(101705918) toll-like receptor 7
  • domestic guinea pig(100713329) toll-like receptor 7
  • Zebrafish(100534776) toll-like receptor 7
  • Horse(791248) toll-like receptor 7
  • domestic cat(493685) toll-like receptor 7
  • chicken(418638) toll-like receptor 7
  • dog(491743) toll-like receptor 7

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Imiquimod, ≥98% (HPLC), solid,
Spezies
human
Imiquimod, United States Pharmacopeia (USP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Hydroxychloroquin -sulfat, ≥98% (HPLC), powder,
Spezies
human
Hydroxychloroquin -sulfat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
2-[4-[(7-Chlor-4-chinolinyl)amino]pentyl]aminoethanol, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
Hydroxychloroquinsulfat -sulfat, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-TLR7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-TLR7 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunocytochemistry

western blot
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-TLR7 Mouse mAb (2C9), liquid, clone 2C9, Calbiochem®,
Speziesreaktivität
human
Anwendung
Monoclonal Anti-TLR7 antibody produced in mouse, clone 2F8, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Tlr7,
Spezies
mouse
MISSION® esiRNA, targeting human TLR7,
Spezies
human