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PYCARD

PYD and CARD domain containing

Synonyme:
ASC, CARD5, TMS, TMS-1, TMS1
Spezies:
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Zebrafish pycard (57923), dog PYCARD (489925), domestic cat PYCARD (101088449), cow PYCARD (282846), sheep PYCARD (101105208), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858)
UniProtKB-ID:
Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8
Gen-ID:
  • Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(66824) PYD and CARD domain containing
  • Rat(282817) PYD and CARD domain containing
  • Zebrafish(57923) PYD and CARD domain containing
  • dog(489925) PYD and CARD domain containing
  • domestic cat(101088449) PYD and CARD domain containing
  • cow(282846) PYD and CARD domain containing
  • sheep(101105208) PYD and CARD domain containing
  • Goat(100861338) PYD and CARD domain containing
  • domestic guinea pig(100734858) PYD and CARD domain containing

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
04-147
Anti-ASC-Antikörper, Klon 2EI-7, clone 2EI-7, from mouse,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
western blot
SAB4501315
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
western blot
SAB5700702
Anti-ASC/TMS1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot
HPA049074
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
SAB5700693
Anti-ASC/TMS1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
EHU066851
MISSION® esiRNA, targeting human PYCARD,
Spezies
human