Direkt zum Inhalt
Merck

POLD2

polymerase (DNA directed), delta 2, accessory subunit

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-POLD2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Inhibitor

Product Number
Beschreibung
Spezies
Cytosin β-D-Arabinofuranosid -hydrochlorid, crystalline,
Spezies
human
Cytarabin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Cytarabin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Cytarabin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Cytarabin, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting human POLD2,
Spezies
human
MISSION® esiRNA, targeting mouse Pold2,
Spezies
mouse