Direkt zum Inhalt
Merck

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Synonyme:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Reversin 205, ≥98% (HPLC), film,
Spezies
mouse, rat, human
D-Cycloserin, synthetic,
Spezies
human
N-Methyl-D-Asparaginsäure, ≥98% (TLC), solid,
Spezies
human, rat
(S)-AMPA, ≥97%,
Spezies
mouse, human, rat
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Ketamin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Acamprosatcalcium, ≥98% (HPLC), powder,
Spezies
human
Acamprosatcalcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Spezies
human
Acamprosatcalcium, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
DL-2-Aminoadipinsäure, ≥99%,
Spezies
rat
2-Phenylchinolin, 99%,
Spezies
rat
Ro 25-6981 hydrochloride hydrate, ≥98% (HPLC), powder,
Spezies
human
Ro 8-4304, solid,
Spezies
human
Spermin, ≥97%,
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Kaninchen-pAb, liquid, Calbiochem®,
Speziesreaktivität
rat
Anwendung
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
horse, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
Anti-NMDAR2B Antibody, clone 5C18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, feline, monkey, mouse, rat
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-GRIN2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Spezies
human
Agmatin -sulfat (Salz), ≥97%, powder,
Spezies
human
Orphenadrin -hydrochlorid, ≥98.0% (AT),
Spezies
human
Orphenadrin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Orphenadrin für die Peakidentifizierung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Pentamidin Isethionatsalz, powder,
Spezies
human
Orphenadrin -hydrochlorid, ≥98.0% (AT),
Spezies
human
Orphenadrin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Orphenadrin für die Peakidentifizierung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
L-Glutaminsäure, ReagentPlus®, ≥99% (HPLC),
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GRIN2B,
Spezies
human
MISSION® esiRNA, targeting mouse Grin2b,
Spezies
mouse